Active substances: Norfloxacin
The overall rate of adverse events in patients treated with fluoroquinolones is roughly similar to that seen in patients treated with other antibiotic classes.
Centers for Disease Control study found patients treated with fluoroquinolones experienced adverse events severe enough to lead to an emergency department visit more frequently than those treated with cephalosporins or macrolides, but less frequently than those treated with penicillins, clindamycin, sulfonamides, or vancomycin.
Among these, tendon problems and exacerbation of the symptoms of the neurological disorder myasthenia gravis are the subject of "black box" warnings in the United States.
Younger people typically experience good recovery, but permanent disability is possible, and is more likely in older patients. Simultaneous use of corticosteroids is present in almost one-third of quinolone-associated tendon rupture.
Fluoroquinoline treatment is associated with risk that is similar to or less than that associated with broad spectrum cephalosporins.
Therefore, cyclosporine serum levels should be monitored and appropriate cyclosporine dosage adjustments made when these drugs are used concomitantly.
Medications Some quinolones exert an inhibitory effect on the cytochrome P-450 system, thereby reducing theophylline clearance and increasing theophylline blood levels. Swallow the tablet with a drink of water.It licensed use in acute and chronic complicated kidney infections has been withdrawn as a result. Medical uses The initial approval by the U.
This is because your body absorbs less norfloxacin after a meal, which means the medicine is less effective. Try to space out the doses over the day - so ideally, take a dose every 12 hours.
Do not drink milk or take indigestion remedies or medicines containing iron or zinc such as multivitamin tablets during the two hours before you take norfloxacin, or during the two hours after you have taken a dose.
This is because these things interfere with the way norfloxacin is absorbed by your body, and stop it from working fully.
If you forget to take a dose, take it as soon as you remember unless your next dose is due.
If your next dose is due then take the dose which is due but leave out the forgotten one.
Do not take two tablets together to make up for a missed dose. Even if you feel your infection has cleared up, keep taking the antibiotic until the course is finished unless you are told to stop by your doctor.
This is to prevent the infection from coming back. If you have a long-term chronic infection, your course of treatment will be for longer than this, possibly for 1-3 months.
If you still feel unwell after finishing the course of tablets, go back to see your doctor. Getting the most from your treatment Remember to keep any routine appointments with your doctor.
This is so your progress can be monitored. Again, they might be sincere, they might even be sane, but not have a real basis for knowing.
I count my blessings controversial day.